Final Data from AlloVir’s Phase 2 Study of Posoleucel for Multi-Virus Prevention to be Highlighted in Oral Presentation at 64th American Society of Hematology Annual Meeting
Posoleucel is AlloVir’s lead investigational virus-specific T cell (VST) therapy being developed as an off-the-shelf therapeutic for the treatment or prevention of up to six devastating viruses (adenovirus, BK virus, cytomegalovirus, Epstein-Barr virus, human herpesvirus-6 and JC virus) that have few to no effective treatment or prevention options and can be life-threatening for allo-HCT patients. These common viral infections present significant challenges in the management of allo-HCT patients, with the potential for prolonged hospitalization, increased risk for graft versus host disease (GVHD), end-organ damage and death. Preventing these viral infections and diseases – whether through the prophylaxis of patients at high risk for viral reactivation or through the preemptive treatment of patients with viral reactivation who have not yet developed clinically significant infections or disease – has the potential to fundamentally transform the treatment landscape for allo-HCT.
“We are excited to share the final data from our Phase 2 study of posoleucel for multi-virus prevention, which continue to support the transformational potential of posoleucel. Based on preliminary data from this study,
Details of the presentation at ASH are as follows:
Final Clinical Outcomes from a Phase 2 Trial of Posoleucel, an Off-the-Shelf, Multivirus-Specific T-Cell Therapy, for the Prevention of Clinically Significant Viral Infections Post-HCT (Abstract 362)
Session 704: Cellular Immunotherapies: Early Phase and Investigational Therapies: CAR T in Multiple Myeloma and T-cell Therapies After Allo-HCT
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